Muscle Physiology

Types of Muscle

l    Skeletal

l   Provides for body movement

 

l    Smooth

l   Provides for appropriate distribution of blood flow during exercise

 

l    Cardiac

l   Provides appropriate distribution of blood flow for body functions

Connective Tissue of Skeletal Muscle

l   Epimysium

l   Outer covering that is continuous with tendons

l   Covers all 430 skeletal muscles in body

l   Perimysium

l   Outer covering for fasciculi (bundles of muscle fibers

l   Endomysium

l   Outer covering for each muscle fiber

The Muscle Fiber

l    Contains hundreds to thousands of myofibrils

l   Contain the apparatus to contract the muscle fiber

l   Apparatus include:

l   Sarcoplasmic Reticulum
l   Transvers Tubule – area of calcium storage
l   Longitudinal Tubule - roadway for calcium transport to myofilaments
l   Myofilaments
l   Actin
l   Myosin
     - crossbridge connection
 

Muscle Contraction

l         Process

l        Signal from brain and/or spinal cord

l        Signal moves along nerve to neuromuscular junction

l        Ach in junction transports message to muscle

l        Electrical activity in muscle signals calcium to be released from area of transverse tubule

l        Calcium moves through longitudinal tubule

The Neuromuscular Junction

l   Gap between the nerve ending and muscle fiber

Muscle Contraction

l    Process continues

6. Calcium binds to troponin

7. Tropomyosin (inhibitory protein) moves out of way to allow myosin crossbridge to connnect to actin

8. Myosin crossbridge connects to actin

9. ATP is broken down and releases energy

10. Crossbridge moves actin inward causing shortening of muscle fiber 

11. Ratcheting effect continues until contraction is complete

 

Types of Contraction

l    Isometric

l   Developing tension in the muscle without a change in muscle length

l    Isotonic

l   Developing tension in the muscle with a change in muscle length

l   Concentric – shortening

l   Eccentric – lengthening

l    Isokinetic

l   Developing tension in the muscle that is met by an equal opposing resistance

 

Force Production

l    Dependent upon:

l    Number of crossbridges connected to actin at any instant in time

l   Preloaded or unpreloaded state

l   Eg. When lifting a barbell, isometric contraction is needed to hold the weight (preloaded)

l   Eg. When lifting with hydraulic or isokinetic systems (unpreloaed)

l   Cross-sectional area – size matters

l   Velocity of shortening

l   Less force production is possible the faster the contraction

 

Force Production

l   Dependent upon:

l    Angle of pennation (arrangement of fibers)

l  3 types

l   Muscle fibers run parallel
l   One set of muscle fibers are oblique to tendon
l   Muscle fibers are aligned at oblique angle on both sides of tendon

l   Sarcomere Length

l   Prestretching

l  Can enhance force of a concentric contraction

l   Due to elasticity and stretch-shortening phenomenon

 

 

Force Production

l    Dependent upon:

l    Exercise-induced muscle damage

l   Hard exercise can lead to DOMS (delayed onset of muscle soreness)

l   Occurs 24-48 hours after hard exercise

l   Most likely due to tearing of muscle and connective tissue

l   Age of muscle

l   Sarcopenia – reduced muscle size and strength

l   Fiber Type

l   Fast-twitch

l   Slow-twitch